|Payment Terms:||L/C,D/P,T/T,Western Union,MoneyGram|
|Supply Ability:||300 Kilogram/Kilograms per Month|
|Other Names:||Tianeptine sodium|
|Place of Origin:||China|
|Type:||Auxiliaries and Other Medicinal Chemicals|
|Grade Standard:||Medicine Grade|
|Product Name:||Tianeptine sodium salt|
|Appearance:||White to off-white powder|
|Name:||Tianeptine sodium salt powder|
High purity Tianeptine sodium salt
for Antidepressant 30123-17-2
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake . Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).