| Port: | Xi'an, Shanghai, Tianjin and so on |
| Payment Terms: | L/C,D/A,D/P,T/T,Western Union,MoneyGram |
| Supply Ability: | 5000 Kilogram/Kilograms per Month Gliclazide Supply Capacity |
| Other Names: | Gliclazide |
| Usage: | Animal Pharmaceuticals |
| Place of Origin: | Shaanxi China |
| Molecular Weight: | 323.41 |
| Grade Standard: | Feed Grade,Food Grade,Medicine Grade,Tech Grade |
| Solubility: | methylene chloride: soluble |
| Product Name: | Gliclazide |
| Purity: | 99%min |
| Shelf life: | 2 Years Properly Stored |
| Model Number: | TGY-Gliclazide |
| Density: | 1.2205 (rough estimate) |
| Appearance: | White powder |
| CAS No.: | 21187-98-4 |
| Brand Name: | TGY |
| Type: | Anti-Allergic Agents,Antibiotic and Antimicrobial Agents,Vitamins, Amino Acids and Coenzymes,Auxiliaries and Other Medicinal Chemicals,Antihypertensive |
| Storage: | -20°C Freezer |
| Test Method: | HPLC |
| EINECS No.: | 244-260-5 |
| MF: | C15H21N3O3S |
| Application: | Pharmaceutical raw materials |
| Melting point: | 163-169 °C(lit.) |
| Packaging Detail: | Anti-diabetic Drug Gliclazide Powder CAS 21187-98-4 Gliclazide Package 1-5kg with ziplock plastic bag inside,Aluminum foil bag outside.finally with waterproof bag. 6-15kg with plastic bag inside,Aluminum foil bag outside,finally with carton box. More than 16kg with plastic bag inside,fiber drum outside according to the extract quantity. |
| Package Preview: | https://sc04.alicdn.com/kf/HTB1KQx0dRKw3KVjSZTEq6AuRpXaB.jpg_640x640.jpg,https://sc04.alicdn.com/kf/HTB1yYekawFY.1VjSZFqq6ydbXXas.jpg_640x640.jpg |
Anti-diabetic Drug Gliclazide Powder CAS 21187-98-4 Gliclazide
Gliclazide CAS No.21187-98-4 Basic Information:
| Product Name | Gliclazide |
| Synonyms | )-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea; |
| CAS | 21187-98-4 |
| MF | C15H21N3O3S |
| MW | 323.41 |
| EINECS | 244-260-5 |
| Product Categories | Pharmaceutical;Active Pharmaceutical Ingredients; |
Gliclazide CAS No.21187-98-4 Chemical Properties:
| Melting point | 163-169 °C(lit.) |
| refractive index | 1.6740 (estimate) |
| density | 1.2205 (rough estimate) |
| storage temp. | -20°C Freezer |
| Merck | 14,4439 |
Gliclazide CAS No.21187-98-4 Spec.:
|
Items |
Standard |
Test Result |
|
Appearance |
White crystalline powder |
Confirm |
|
Residue on ignition |
0.10%Max |
<0.01% |
|
Heavy metals |
0.001% Max |
<0.0005% |
|
Melting point |
108.0-110.0ºC |
108.5ºC |
|
Water Content |
0.20%Max |
0.14% |
|
Mesh size |
80-100mesh |
80-100mesh |
|
Assay |
99.9%Min |
99.92% |
|
Salmonella |
Negative |
Negative |
|
Staphylococcus |
Negative |
Negative |
COA
|
Items |
Acceptable criteria |
Results |
|
Characteristics |
A white or almost white powder |
A white powder |
|
Solubility |
Practically insoluble in water: freely soluble in methylene chloride; Sparingly soluble in acetone(96%); slightly soluble in alcohol (96%) |
Conforms |
|
M.P |
162-166°C |
164.0-164.5°C |
|
Identification |
Conform to the spectrum of the CRS Gliclazide |
Conforms |
|
Heavy metals |
≤10ppm |
<10ppm |
|
Impurity B |
≤2ppm |
0.3ppm |
|
Related substances |
Impurity F ≤0.10% |
<0.10% |
|
Other single impurity ≤0.10% |
<0.10% |
|
|
Total of other impurities ≤0.2% |
0.13% |
|
|
Loss on drying |
≤0.25% |
0.1% |
|
Sulphated ash |
≤0.1% |
0.01% |
|
Residual solvents |
Ethyl acetate ≤0.5% |
Below LOQ |
|
Toluene ≤0.089% |
Below LOQ |
|
|
Assay (on dried basis) |
99.0%-101.0% |
99.5% |
|
Conclusion |
The test results conform with EP7.0/BP2009 |
|
Gliclazide is an anti-diabetic medication used to treat diabetes mellitus type 2. It is used when dietary changes, exercise, and weight loss are not enough. It is taken by mouth.
Gliclazide was patented in 1966 and approved for medical use in 1972. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 2.46 to 3.92 USD per month. In the United Kingdom a month of medication costs the NHS about 2.12 pounds. It is not available for sale in the United States.Fall blood sugar medicine, used in the treatment of non insulin dependent diabetes
It is mainly used for adult onset diet alone invalid, and no diabetes ketosis tendency of light duty.
Also improve diabetics fundus diseases and metabolic disorder of blood vessel function.
