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Anti-diabetic Drug Gliclazide Powder CAS 21187-98-4 Gliclazide

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Port: Xi'an, Shanghai, Tianjin and so on
Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram
Supply Ability: 5000 Kilogram/Kilograms per Month Gliclazide Supply Capacity
Other Names: Gliclazide
Usage: Animal Pharmaceuticals
Place of Origin: Shaanxi China
Molecular Weight: 323.41
Grade Standard: Feed Grade,Food Grade,Medicine Grade,Tech Grade
Solubility: methylene chloride: soluble
Product Name: Gliclazide
Purity: 99%min
Shelf life: 2 Years Properly Stored
Model Number: TGY-Gliclazide
Density: 1.2205 (rough estimate)
Appearance: White powder
CAS No.: 21187-98-4
Brand Name: TGY
Type: Anti-Allergic Agents,Antibiotic and Antimicrobial Agents,Vitamins, Amino Acids and Coenzymes,Auxiliaries and Other Medicinal Chemicals,Antihypertensive
Storage: -20°C Freezer
Test Method: HPLC
EINECS No.: 244-260-5
MF: C15H21N3O3S
Application: Pharmaceutical raw materials
Melting point: 163-169 °C(lit.)
Packaging Detail: Anti-diabetic Drug Gliclazide Powder CAS 21187-98-4 Gliclazide Package 1-5kg with ziplock plastic bag inside,Aluminum foil bag outside.finally with waterproof bag. 6-15kg with plastic bag inside,Aluminum foil bag outside,finally with carton box. More than 16kg with plastic bag inside,fiber drum outside according to the extract quantity.
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Product Description

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Anti-diabetic Drug Gliclazide Powder CAS 21187-98-4 Gliclazide

 

 

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Gliclazide CAS No.21187-98-4 Basic Information:

 Product Name  Gliclazide
 Synonyms  )-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;
 CAS  21187-98-4
 MF  C15H21N3O3S
 MW  323.41
 EINECS  244-260-5
 Product Categories  Pharmaceutical;Active Pharmaceutical Ingredients;

Gliclazide CAS No.21187-98-4 Chemical Properties:

Melting point   163-169 °C(lit.)
refractive index   1.6740 (estimate)
density   1.2205 (rough estimate)
storage temp.    -20°C Freezer
Merck   14,4439

Gliclazide CAS No.21187-98-4 Spec.:

Items

Standard

Test Result

Appearance

 White crystalline powder

Confirm

Residue on ignition

 0.10%Max

<0.01%

Heavy metals

 0.001% Max

<0.0005%

Melting point

 108.0-110.0ºC

 108.5ºC

Water Content

 0.20%Max

0.14%

Mesh size

 80-100mesh

80-100mesh

Assay

 99.9%Min

99.92%

Salmonella

 Negative

Negative

Staphylococcus

 Negative

Negative

 

 COA

 

Items

Acceptable criteria

Results

Characteristics

A white or almost white powder

A white powder

Solubility

Practically insoluble in water: freely soluble in methylene chloride;

Sparingly soluble in acetone(96%); slightly soluble in alcohol (96%)

Conforms

M.P

162-166°C

164.0-164.5°C

Identification

Conform to the spectrum of the CRS Gliclazide

Conforms

Heavy metals

≤10ppm

<10ppm

Impurity B

≤2ppm

0.3ppm

Related substances

Impurity F ≤0.10%

<0.10%

Other single impurity ≤0.10%

<0.10%

Total of other impurities ≤0.2%

0.13%

Loss on drying

≤0.25%

0.1%

Sulphated ash

≤0.1%

0.01%

Residual solvents

Ethyl acetate ≤0.5%

Below LOQ

Toluene ≤0.089%

Below LOQ

Assay (on dried basis)

99.0%-101.0%

99.5%

Conclusion

The test results conform with EP7.0/BP2009

 

 

Gliclazide is an anti-diabetic medication used to treat diabetes mellitus type 2. It is used when dietary changes, exercise, and weight loss are not enough. It is taken by mouth.

Gliclazide was patented in 1966 and approved for medical use in 1972. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 2.46 to 3.92 USD per month. In the United Kingdom a month of medication costs the NHS about 2.12 pounds. It is not available for sale in the United States.
 
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Fall blood sugar medicine, used in the treatment of non insulin dependent diabetes

It is mainly used for adult onset diet alone invalid, and no diabetes ketosis tendency of light duty.

Also improve diabetics fundus diseases and metabolic disorder of blood vessel function.

 
1. For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions.
2. Hypoglycemic agents. It can be used for the treatment of non-insulin dependent diabetes mellitus.
3. Hypoglycemic agents, non-insulin dependent diabetes mellitus.
 
 
 
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