Ciprofloxacin HCL is the most widely used of the second-generation quinolones.In 2010, over 20 million prescriptions were written, making it the 35th-most commonly prescribed generic drug and the 5th-most commonly prescribed antibacterial in the U.S.
Items of analysis
Residue on ignition
Ciprofloxacin ethylenediamine analog
Any other individual impurity
The sum of all impurities
Conclusion:Conforms to USP42 specification for Ciprofloxacin Hydrochloride
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USE: pharmaceutical raw material Ciprofloxacin HCl drug is used for the treatment of Bacterial infection of Respiratory tract, UTI, Uncomplicated Cystitis in females, GI, Chronic Bacterial Prostatitis, CNS, Immuno compromised patients, Skin, Bone and Joint Infections, Uncomplicated cervical and urethral gonorrhea.
Ciprofloxacin HCl drug has in vitro activity against a wide range of gram-negative and gram-positive organisms.
Ciprofloxacin HCl drug inhibits bacterial DNA gyrase, an enzyme responsible for counteracting excessive supercoiling of DNA during replication or transcription. The mechanism of action of quinolones, including
Ciprofloxacin HCl drug, is different from that of other antimicrobial agents such as beta-lactams, macrolides, tetracyclines, or aminoglycosides; therefore, organisms resistant to these drugs may be susceptible to Ciprofloxacin HCl drug. There is no known cross-resistance between ciprofloxacin HCl drug and other classes of antimicrobials.
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