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Top Quality Recombinant Human Growth Differentiation Factor 11

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Port: Shenzhen China
Payment Terms: T/T
Other Names: Bone Morphogenetic Protein 11
Usage: Animal Pharmaceuticals
Water soluble: Soluble
Place of Origin: Guangdong China
Grade Standard: Medicine Grade
Sample: Availiable
Product Name: Growth Differentiation Factor 11
Purity: 95%
Grade: Comestic Grade
Model Number: hearan-055
Appearance: White Freeze Dried Powder
MOQ: 200mg
CAS No.: 827267-17-4
Brand Name: Hearan
Function: Anti-aging
Type: Vitamins, Amino Acids and Coenzymes
Storage: Freezer
EINECS No.: NA
MF: C221H366N72O67S
Shelf Life: 2 Years
Application: Cosmetic Raw Materials
Packaging Detail: Customization accroding to requirement
Guangzhou Hearan Biotechnology Co., Ltd.
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★  Product Description
Product Name
Growth Differentiation Factor 11
Derivation
Human resource recombinant
Purity
95%
Usage
Cosmetic Biological engineering
Storage
2-8℃
Type
Raw material
CAS
827267-17-4
Form
Sterile Filtered White lyophilized powder
About GDF-11
Growth differentiation factor 11(GDF-11) is a secreted protein, also known as bone morphogenetic protein 11(BMP-11),which belongs to the transforming growth factor beta(TGF-b) superfamily and is closely related to GDF-8. GDF-11 controls anterior/posterior axis during development. GDF-11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin,including stopping the progenitor cell-cycle during G-phase.The similarities between GDF-11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.GDF-11 controls anterior/posterior axis during development.
Systemic GDF-11 levels decline with age, and administration of higher levels of GDF-11 can reverse age-related cardiac
hypertrophy. In addition, systemic administration of recombinant GDF-11 protein restores genomic integrity and health of muscle stem cells and neurovasculature and also enhances neurogenesis. Recent findings show that GDF-11 has rejuvenating properties with pronounced effects on the cardiovascular system, brain, skeletal muscle, and skeleton. Several human studies were also conducted, some implicating decreasing levels of circulating GDF-11 with age. The effect of recombinant GDF-11 on the function of various skin cells was examined in human epidermal keratinocytes, dermal fibroblasts, melanocytes, dermal microvascular endothelial cells and 3D skin equivalents, as well as in ex vivo human skin explants. Important role for GDF11 in skin biology and a potential impact on skin health and aging.
★ Effect
1.Treat muscle atrophy, strengthen muscle toughness,Increase muscle number. 2.Treating malnutrition patients is an important index of the strength training athletes. 3.GDF-11 can effectively prevent the increased due to age brings the increase of adipose tissue, and reduce the occurrence of diabetes and obesity.
★ Product Application
1) Myostatin / GDF-11 can effectively prevent the increased due to age brings the increase of adipose tissue, and reduce the occurrence of diabetes and obesity. 2) Myostatin / GDF-11 used to treating malnutrition patients is an important index of the strength training athletes. 3) Myostatin / GDF-11 used to treat muscle atrophy, strengthen muscle toughness,Increase muscle number.
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