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GMP Factory Supply API raw material sildenafil powder for sex enhance CAS 139755-83-2

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Port: China main port
Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram
Supply Ability: 2000 Kilogram/Kilograms per Month
Other Names: SIDANAFIL
Place of Origin: China
Molecular Weight: 474.576
Grade Standard: Medicine Grade
Product Name: Sildenafil powder
Purity: 99%
Shelf life: 2 Years
Grade: Phamaceutical Grade
Model Number: /
Appearance: White Crystalline Powder
CAS No.: 139755-83-2
Brand Name: Virgin
Assay: 99%min
Type: Auxiliaries and Other Medicinal Chemicals
Test Method: HPLC
CAS: 139755-83-2
EINECS No.: /
MF: C22H30N6O4S
Molecular Formula: C22H30N6O4S
Certificate: ISO9001
Packaging Detail: 1kg/bag (Inner: plastic bag .outer: Aluminum foil bag ); 5kg/carton (Inner: Double plastic bags. Outer: Carton); 10kg/carton (Inner: Double plastic bags. Outer: Carton); 25kg/drum (Inner: Double plastic bags. Outer: Fiber drum); Others: According to customer demand. Cool and dry place, keep away from strong light
Package Preview: https://sc04.alicdn.com/kf/H8d1fbd9203e64a839e00646f6558296cG.jpg_640x640.jpg
Xi'an Virgin Biological Technology Co., Ltd.
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Response Rate
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On-time delivery rate
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Employees
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GMP Factory Supply  API raw material  sildenafil powder  for sex enhance CAS 139755-83-2 

Product Description

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Product Name   
 Sildenafil Citrate Powder
Other Name
Sildenafil tablets;Sideennafil;Sildenafil Citrate;SildenatllCitrate;Sildenafil Citrate Tablets;VIAGRA
CAS
139755-83-2 
Appearance
White crystalline powder
Density
1.39g/cm3 
Melting Point
187-189°C 
Boiling Point
672.4°C  at 760 mmHg
Flashing Point
360.5°C 

 

 

Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erectction. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily. Sildenafil relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body. Another function is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

 

Sildenafil .jpg

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This product is an oral medication for penile erectile dysfunction (ED). It is a citrate of sildenafil, a selective inhibitor of type 5 phosphodiesterase (PDE5) specific to cyclic guanosine monophosphate (cGMP).

Mechanism of action:  The physiological mechanism of penile erection involves the release of nitric oxide (NO) in the penile sponge during sexual stimulation. NO activates guanylate cyclase, resulting in increased levels of cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscles in the sponge and fills the blood. Pharmacodynamics Sildenafil's effect on penile erection: Sildenafil is a highly selective phosphodiesterase 5 (PDE5) inhibitor. PDE5 is highly expressed in the corpora cavernosa and in other tissues. (Including platelets, blood vessels and visceral smooth muscle, skeletal muscle), low expression. Sildenafil selectively inhibits PDE5, enhances the nitric oxide (NO) -cGMP pathway, increases cGMP levels and causes smooth muscle relaxation of the cavernous body of the penis, making patients with erectile dysfunction have a natural erectile response to sexual stimulation. Erectile response generally increases with increasing sildenafil dose and plasma concentration. Experiments show that the effect lasts up to 4 hours, but the response is weaker than that at 2 hours. Sildenafil's response to the myocardium: PDE5 does not exist in normal or diseased cardiac conductive tissues, cardiomyocytes, endothelial cells, and lymphoid tissues, so sildenafil (PDE5 inhibitors) have no positive inotropic effect and cannot Directly affect myocardial contractility.

 

 

 

 

 

 

 

 

 

 

Certifications

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